Active constituents
The active constituents in anise, particularly the terpenoid anethole, are contained in its
volatile oil. The volatile oil gives the plant a delightful flavor and has been combined with
other less pleasant tasting medicinal herbs to offset their taste. The oil is also
antispasmodic, helping to relieve intestinal gas and
spasmodic coughs.3 Anise has been combined with
cathartic laxatives to help reduce the spasmodic cramping they can cause.4 It may
also have modest antiparasitic actions and has been recommended by some practitioners to treat
mild intestinal parasite infections.5
Anethole has been documented to have phytoestrogen activity in test tubes and
animals;6 the relevance of this to humans is unknown. No clinical trials have been
conducted to support any of these uses, though anise is approved for use by the German
Commission E for relieving coughs and indigestion.7
Are there any side effects or interactions?
There are no known adverse effects from anise other than occasional allergic reactions of
the skin with topical use and of the respiratory or gastrointestinal tract with internal use.
It is frequently used to alleviate cough in children because of its gentleness and pleasant
taste.10 The safety of using anise during
pregnancy and breast-feeding is
unknown, though it is very likely safe and has traditionally been used to support
breast-feeding in some cultures.11
At the time of writing, there were no well-known drug interactions
with anise.
References
1. Chopra RN, Chandler AC. Anthelmintics and Their Uses in Medical
and Veterinary Practice. Baltimore: Williams & Wilkins Co, 1928:159.
2. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and
Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
3. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and
Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
4. Mills SY. Out of the Earth: The Essential Book of Herbal
Medicine. Middlesex, UK: Viking Arkana, 1991:290
5. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and
Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
6. Albert-Puleo M. Fennel and anise as estrogenic agents. J
Ethnopharm 1980;2:337–44.
7. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American
Botanical Council and Boston: Integrative Medicine Communications, 1998:82–3.
8. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and
Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
9. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American
Botanical Council and Boston: Integrative Medicine Communications, 1998:82–3.
10. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum
and Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
11. Bingel AS, Farnsworth NR. Higher plants as potential sources of
galactagogues. Econ Med Plant Res 1994;6:1–54 [review].
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